Can i take lasix if allergic to sulfa

On one side, a large cohort study shows some cross-reactivity. Reasonable evidence supports what many of us are doing: Using cheap thiazides for patients with a history of sulfa allergy.

Patients were identified as being allergic using both narrow definitions anaphylaxis, bronchospasm, urticaria, laryngospasm, or angioedema and broad ones. As only 18 patients out of the 20, patients were reported as having an allergic reaction using the narrow definition, analysis was based on the broad definition.

Using this broad definition, researchers identified allergies to sulfonamide antibiotics in patients. Of this group, 96 patients 9. It was unclear if any patients taking a carbonic anhydrase inhibitor experienced an allergic reaction. For comparison purposes, of the 19, patients who were not identified as having an allergy to a sulfonamide antibiotic, again using the broad definition, 1.

When the results were adjusted for age, sex, history of asthma, use of medications for asthma or corticosteroids, the adjusted odds ratio for individuals experiencing an allergy to a nonantibiotic sulfonamide in those persons with a history of allergy to a sulfonamide antibiotic was 2.

Clinicians should conduct a careful risk-benefit assessment before prescribing, taking into account the history and nature of the allergy and any other drugs the patient may have taken, as it is possible they will have taken another sulfonamide in the interim period without it being realised.

Patients will need to be counselled and monitored. Any decision to prescribe needs to be in the knowledge that if use of a drug is contraindicated, the prescriber is taking responsibility. Advertising revenue supports our not-for-profit mission.

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